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HORMONE THERAPY

Bioidentical Hormones Explained

Dr. Alexander Landfield

Board-Certified Neurologist & Medical Director

March 9, 2026
Hormone Therapy

Bioidentical hormones have become a preferred option for many patients and physicians in the field of hormone replacement therapy. At Rani Beauty Clinic in Renton, WA, Dr. Alexander Landfield uses bioidentical hormones as the foundation of his hormone therapy programs because of their compatibility with the human body and their favorable safety profile.

Bioidentical hormones are defined by their molecular structure — they are chemically identical to the hormones naturally produced by the human body. Bioidentical estradiol has the exact same molecular structure as the estradiol produced by the ovaries. Bioidentical testosterone is structurally identical to the testosterone produced by the testes and adrenal glands. This structural match means that bioidentical hormones bind to hormone receptors and are metabolized by the body in the same way as naturally produced hormones.

Synthetic hormones, by contrast, have been chemically modified. These modifications were originally developed to make hormones patentable by pharmaceutical companies. While synthetic hormones do activate hormone receptors, their altered molecular structure means they are metabolized differently by the body and may produce different metabolic byproducts. Some of the adverse effects observed in early hormone therapy studies, including the Women's Health Initiative, have been attributed to the use of synthetic hormones rather than bioidentical formulations.

Bioidentical hormones are available in multiple delivery forms, including creams, gels, patches, pellets, and injections. They can be obtained through commercial FDA-approved products or through compounding pharmacies that create customized formulations tailored to individual patient needs. At Rani Beauty Clinic, Dr. Landfield selects the delivery method and formulation that best serves each patient's physiology, preferences, and lifestyle. Regular monitoring through blood work ensures that hormone levels reach and remain at optimal targets. Whether you are a man seeking testosterone optimization or a woman navigating perimenopause, bioidentical hormones offer a physiologically compatible approach to restoring hormonal balance.

FREQUENTLY ASKED QUESTIONS

Common Questions

Bioidentical hormones have the exact same molecular structure as hormones naturally produced by the human body. This means they bind to receptors and are metabolized identically to your own hormones, unlike synthetic hormones that have been chemically modified.

Many physicians consider bioidentical hormones to have a more favorable safety profile because they are metabolized naturally by the body. Some adverse effects seen in studies using synthetic hormones have not been replicated with bioidentical formulations. Individual risk factors should still be evaluated.

Yes. Bioidentical hormones, whether commercial or compounded, are prescription medications that require physician supervision. At Rani Beauty Clinic, Dr. Landfield prescribes bioidentical hormones based on comprehensive blood work and clinical evaluation.

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