Dr. Alexander Landfield
Board-Certified Neurologist & Medical Director
Platelet-Rich Plasma (PRP) therapy uses the healing components of your own blood to stimulate tissue regeneration. At Rani Beauty Clinic in Renton, WA, Dr. Landfield offers PRP for skin rejuvenation and hair restoration based on the well-established science of platelet biology.
What platelets do: Platelets are cell fragments produced by megakaryocytes in the bone marrow. While they are best known for their role in blood clotting, platelets are packed with growth factors and signaling molecules that play a central role in tissue repair and regeneration. When tissue is injured, platelets are among the first responders, releasing their cargo of growth factors to initiate and coordinate the healing process.
The growth factor payload: Each platelet contains granules filled with bioactive proteins including Platelet-Derived Growth Factor (PDGF), which stimulates cell proliferation and blood vessel formation. Transforming Growth Factor-Beta (TGF-B), which promotes collagen synthesis and tissue remodeling. Vascular Endothelial Growth Factor (VEGF), which stimulates new blood vessel formation. Epidermal Growth Factor (EGF), which promotes skin cell growth and differentiation. Insulin-Like Growth Factor (IGF), which supports cell growth and differentiation.
How PRP is prepared: A small volume of your blood (typically 10 to 30 mL) is drawn and placed in a centrifuge. The centrifuge spins the blood at high speed, separating it into layers by density. The platelet-poor plasma rises to the top, red blood cells settle to the bottom, and the platelet-rich layer concentrates in the middle. This platelet-rich layer is collected, producing a preparation with three to five times the normal platelet concentration.
PRP for skin rejuvenation: When PRP is injected into the skin or applied after microneedling, the concentrated growth factors stimulate fibroblast activity, increasing collagen and elastin production. The growth factors also promote angiogenesis (new blood vessel formation), which improves circulation and nutrient delivery to the treated skin. Over weeks to months, these effects produce improved skin texture, tone, firmness, and overall quality.
PRP for hair restoration: In hair restoration applications, PRP is injected into the scalp at the level of the hair follicles. The growth factors stimulate the dermal papilla cells that control hair growth, potentially prolonging the anagen (growth) phase, increasing blood supply to the follicles, and creating a more favorable environment for hair growth. Clinical studies have shown increased hair count and thickness in patients receiving PRP treatment.
The autologous advantage: Because PRP is derived from your own blood, there is virtually no risk of allergic reaction, rejection, or disease transmission. The treatment is inherently biocompatible. The growth factors in your PRP are the same molecules your body naturally uses for healing and repair, just in higher concentrations.
Combination protocols: PRP is often combined with other treatments for enhanced results. PRP with microneedling combines the collagen-stimulating effect of microneedling with the growth factor delivery of PRP. PRP with RF microneedling adds the thermal collagen stimulus to the growth factor effect. PRP after laser treatment supports faster healing and enhanced regeneration.
Treatment series: Most PRP protocols involve a series of three to four treatments spaced four to six weeks apart for skin rejuvenation, or three to four treatments spaced one month apart for hair restoration. Maintenance treatments every six to twelve months sustain and build on the results. Individual response varies based on age, health status, and the specific concern being treated.
The evidence base: PRP has been used in orthopedic medicine, dentistry, and wound healing for over two decades. Its application in aesthetics and hair restoration is supported by a growing body of clinical evidence showing improvement in skin quality, wrinkle reduction, and hair growth parameters. The quality of evidence continues to improve as more controlled studies are published.
