GLP-1 Weight Management
Transform your relationship with weight through science-backed GLP-1 therapy. The Rani Protocol combines FDA-approved medications — Semaglutide and Tirzepatide — with in-house blood work, physician supervision by Dr. Alexander Landfield, and personalized support to help you achieve meaningful, sustainable weight loss.
What Is GLP-1 Weight Management?
How It Works
Initial Consultation & Eligibility Assessment
Your journey begins with a comprehensive medical consultation. Our medical team evaluates your health history, current medications, BMI, and weight loss goals to determine if GLP-1 therapy is appropriate for you. Generally, candidates have a BMI of 30+ (obese) or BMI of 27+ (overweight) with at least one weight-related comorbidity such as type 2 diabetes, hypertension, high cholesterol, or obstructive sleep apnea. We discuss both Semaglutide and Tirzepatide options so you can make an informed choice.
In-House Blood Work & Baseline Labs
Before starting medication, we perform comprehensive blood work right here in our clinic — no need to visit a separate lab. Our baseline panel typically includes a comprehensive metabolic panel (CMP), lipid panel, thyroid function (TSH), hemoglobin A1c, fasting glucose, liver function tests, and kidney function markers. These labs establish your metabolic baseline, screen for contraindications, and provide data points for tracking your health improvements throughout the program. Dr. Landfield reviews all lab results personally.
Medication Initiation & Dose Titration
You begin at a low dose and gradually titrate up over several weeks to minimize gastrointestinal side effects and allow your body to adjust. For Semaglutide, the typical titration schedule starts at 0.25mg weekly for 4 weeks, then increases to 0.5mg, 1.0mg, 1.7mg, and up to 2.4mg based on tolerance and response. Tirzepatide follows a similar gradual titration protocol. Your clinician monitors your response at each dose level and adjusts the timeline based on how your body responds.
Ongoing Monitoring & Support
The Rani Protocol includes regular check-ins with your medical team — typically every 4 weeks during the titration phase and every 4–8 weeks once you reach your maintenance dose. At each visit, we assess weight loss progress, medication tolerance, side effects, nutritional status, and overall health. Follow-up blood work is performed at regular intervals (typically every 3 months) to monitor metabolic markers and ensure safety. Dr. Landfield reviews all follow-up labs and treatment plans.
Maintenance & Long-Term Strategy
As you approach your goal weight, we work with you to develop a long-term maintenance strategy. This may include continued medication at a maintenance dose, gradual tapering, and sustainable lifestyle modifications to preserve your results. Our goal is not just weight loss — it is lasting health transformation with ongoing medical support.
Who Is It For?
- Adults with a BMI of 30 or higher (obese) seeking effective, physician-supervised weight loss
- Adults with a BMI of 27 or higher (overweight) with at least one weight-related health condition such as type 2 diabetes, hypertension, or high cholesterol
- Individuals who have struggled to lose weight through diet and exercise alone
- Those who have experienced weight regain after previous successful weight loss
- People seeking a medically-supervised, evidence-based approach rather than fad diets or unsupervised programs
- Individuals who want comprehensive health monitoring — including blood work and metabolic tracking — alongside their weight loss program
- Those who prefer a local, in-person medical team over telehealth-only weight loss services
What to Expect
Before
Before your first appointment, gather information about your medical history, current medications, previous weight loss attempts, and health goals. Plan to fast for 10–12 hours before your visit if blood work will be drawn at your initial appointment (your scheduling coordinator will advise you). Your initial consultation will take approximately 45–60 minutes, including the medical evaluation, blood draw, and discussion of medication options. There is no need to start any specific diet before your first visit — we will develop a sustainable nutritional approach together as part of The Rani Protocol.
During
The GLP-1 medication is administered via a small, pre-filled injection pen that you self-administer once weekly at home. At your initial visit, our team will teach you the proper injection technique — the injection uses an ultra-fine needle and is administered subcutaneously (under the skin) in the abdomen, thigh, or upper arm. Most patients describe it as a brief pinch that takes only seconds. You will choose a consistent day of the week for your injection. During your regular follow-up visits (typically 15–30 minutes), your clinician will review your progress, address any concerns, and adjust your dose as needed.
After
Most patients begin noticing reduced appetite and early weight loss within the first 2–4 weeks. Gastrointestinal side effects — including nausea, decreased appetite, constipation, and occasional diarrhea — are the most common side effects and are typically mild to moderate, occurring most frequently during dose increases. These side effects usually diminish as your body adjusts to each new dose level. To minimize nausea, eat smaller, more frequent meals, stay hydrated, and avoid high-fat and greasy foods. Your medical team is available between visits if you experience any concerns. Significant weight loss — typically 5–10% of body weight — is often achieved within the first 3 months, with continued loss over the following 6–12 months.
Results & Recovery
Clinical trial data for Semaglutide 2.4mg demonstrates an average weight loss of approximately 15% of total body weight over 68 weeks. Tirzepatide at the highest dose has shown average weight loss of up to 22.5% of body weight. Individual results vary based on starting weight, adherence, lifestyle modifications, and metabolic factors. Beyond weight loss, patients often experience improvements in blood sugar control, blood pressure, cholesterol levels, energy, sleep quality, and joint pain. The Rani Protocol is designed for lasting results — our comprehensive approach, including regular monitoring, lab work, and ongoing medical support, helps you not only lose weight but maintain your results long-term. There is no surgical recovery or downtime — GLP-1 therapy integrates seamlessly into your daily life.
Why Rani for GLP-1 Weight Management
The Rani Protocol is fundamentally different from telehealth weight loss services that mail you medication with minimal medical oversight. At Rani Beauty Clinic, your GLP-1 weight management program is supervised by Dr. Alexander Landfield, a board-certified neurologist and our Medical Director. We perform comprehensive blood work in-house — you never need to visit a separate lab — and Dr. Landfield personally reviews every set of lab results. Our medical team monitors your health at every step, adjusting your protocol based on your body's response and your metabolic markers. We provide the in-person, physician-supervised care that weight management medicine demands, in a welcoming and supportive environment. We treat weight management as the serious medical endeavor it is, combining pharmaceutical innovation with thorough clinical oversight.
Pricing
Contact us for personalized pricing. We offer competitive rates and flexible financing through Cherry and PatientFi.
Frequently Asked Questions
What is the difference between Semaglutide and Tirzepatide?+
Both are injectable medications that reduce appetite and promote weight loss, but they work through slightly different mechanisms. Semaglutide is a GLP-1 receptor agonist — it mimics the GLP-1 hormone to reduce hunger and increase satiety. Tirzepatide is a dual GIP/GLP-1 receptor agonist, targeting two incretin hormones for potentially greater appetite suppression and metabolic benefit. Clinical trials suggest that Tirzepatide may produce slightly greater weight loss on average (up to 22.5% of body weight vs. approximately 15% for Semaglutide), though individual responses vary. During your consultation, our medical team will discuss both options and help you determine which medication is best suited for your health profile and goals.
Am I eligible for GLP-1 weight management?+
GLP-1 medications for weight management are generally indicated for adults with a BMI of 30 or higher (classified as obese), or adults with a BMI of 27 or higher (classified as overweight) who also have at least one weight-related health condition such as type 2 diabetes, hypertension, dyslipidemia, or obstructive sleep apnea. Contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2 (MEN 2), severe gastrointestinal disease, and pregnancy or planned pregnancy. Our medical team conducts a thorough health assessment and blood work to determine your eligibility and ensure safety.
What are the side effects of GLP-1 medications?+
The most common side effects are gastrointestinal in nature: nausea, decreased appetite, diarrhea, constipation, and occasional vomiting. These side effects are most frequent during dose titration (when the dose is being increased) and typically improve as your body adjusts over 2–4 weeks at each dose level. Our gradual titration protocol is specifically designed to minimize these side effects. Eating smaller, more frequent meals, staying well-hydrated, and avoiding high-fat foods can help manage nausea. Less common side effects may include headache, fatigue, and dizziness. Serious side effects are rare but can include pancreatitis and gallbladder issues. Our regular monitoring and lab work are designed to detect any concerns early.
Why do you require in-house blood work?+
Blood work is a critical component of safe, effective GLP-1 weight management. Baseline labs screen for contraindications (such as thyroid abnormalities or impaired kidney function), establish your metabolic starting point (blood sugar, cholesterol, liver function), and provide objective data for tracking your health improvements throughout the program. Follow-up labs every 3 months allow us to monitor your metabolic response, detect any adverse effects early, and demonstrate the measurable health benefits of your weight loss — not just the number on the scale. We perform all blood draws in-house for your convenience, and Dr. Landfield personally reviews every set of results.
How long do I need to take GLP-1 medication?+
The duration of GLP-1 therapy varies by individual and depends on your weight loss goals, health conditions, and long-term maintenance strategy. Most clinical trials demonstrating significant weight loss were conducted over 52–72 weeks. Some patients may benefit from long-term maintenance dosing to prevent weight regain, while others may be candidates for gradual tapering as they establish sustainable lifestyle habits. Research suggests that weight regain is common after discontinuing GLP-1 medication without ongoing behavioral and nutritional support — which is why The Rani Protocol includes long-term maintenance planning as a core component. Our medical team will work with you to develop an individualized long-term strategy.
How much does the GLP-1 weight management program cost?+
Our GLP-1 weight management programs are structured by medication and dose. Semaglutide starts at $349/month (0.25mg) and scales to $549/month (2.4mg). Tirzepatide starts at $449/month (2.5mg) and scales to $699/month (15mg). Liraglutide starts at $249 per vial. We also offer value packages: the GLP-1 Quick Start is $549 (1st month + starter labs + PeptideVite), the Transform Package (semaglutide) is $1,199 for 3 months, and the Ultimate Package (tirzepatide) is $1,499 for 3 months. All programs include medical consultations, blood work, and ongoing monitoring. We accept HSA/FSA cards, and financing is available through Cherry and PatientFi. Call us at (425) 539-4440 to schedule your initial consultation.
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Ready to Book Your GLP-1 Weight Management?
Call (425) 539-4440 or book online to schedule your consultation.