Dr. Alexander Landfield
Board-Certified Neurologist & Medical Director
Your skin hosts approximately one trillion microorganisms including bacteria, fungi, viruses, and mites that collectively form the skin microbiome. At Rani Beauty Clinic in Renton, WA, Dr. Landfield follows microbiome research because this emerging field is transforming our understanding of skin health, acne, and the optimal approach to skincare.
The skin microbiome is not a passive population but an active ecosystem that influences skin health through multiple mechanisms. Beneficial bacteria compete with pathogenic organisms for resources and space, providing natural infection resistance. They produce antimicrobial peptides that directly kill harmful bacteria. They modulate the immune system's inflammatory response. They influence the skin barrier function.
Cutibacterium acnes, the bacterium most associated with acne, exists on all human skin as part of the normal microbiome. It becomes pathogenic not because of its presence but because of changes in the local environment, particularly the anaerobic, oil-rich conditions within clogged pores, that allow specific acne-causing strains to proliferate while suppressing beneficial strains.
This ecological understanding of acne has important treatment implications. Rather than attempting to sterilize the skin, which disrupts the entire microbiome including beneficial organisms, modern approaches aim to restore ecological balance. Treatments that reduce excess oil and clear clogged pores change the environment that favors pathogenic strains without indiscriminate bacterial destruction.
Common skincare practices can disrupt the microbiome. Harsh cleansers, alcohol-based products, and excessive use of antimicrobial ingredients eliminate beneficial bacteria alongside harmful ones. The resulting dysbiosis, or microbial imbalance, can actually worsen acne, increase sensitivity, and impair barrier function.
Prebiotic and probiotic skincare represents an emerging frontier that works with the microbiome rather than against it. Prebiotic ingredients feed beneficial bacteria. Probiotic ingredients introduce beneficial organisms or their metabolites. While the field is still developing, the principle of supporting rather than disrupting the microbiome is sound.
At Rani Beauty Clinic, our treatment approach respects the microbiome by using targeted rather than indiscriminate antimicrobial strategies and by recommending gentle skincare that maintains microbial diversity.








